![]() ![]() Very common (10% or more): Nausea (14.1%)Ĭommon (1% to 10%): Constipation, vomiting, diarrhea, abdominal pain upper, abdominal pain, dyspepsia, gastritis, gastroenteritis, toothache, gingival bleeding, rectal hemorrhage, dyspepsia, gastrointestinal hemorrhage (including hematemesis and melena), Rare (less than 0.1%): Bleed at critical site Gastrointestinal Uncommon (0.1% to 1%): Postprocedural hemorrhage, hemoglobin decrease of 2 g/dL or more, transfusion of 2 units or more red blood cells, fatal bleed, thrombocytopenia, hemorrhagic anemia Very common (10% or more): Minor bleed (11.7%)Ĭommon (1% to 10%): Anemia postoperative, clinically relevant nonmajor bleed, hemoglobin decreased, anemia, hemorrhage Postprocedural hemorrhage includes postprocedural hematoma, wound hemorrhage, vessel puncture site hematoma, and catheter site hemorrhage. Hemorrhage includes hematoma, and vaginal and urethral hemorrhage. Patients with diabetes had more bleeding events than non-diabetic subjects. Common adverse reactions were anemia, hemorrhage, and nausea. The most common adverse events were related to bleeding. vomiting of blood or material that looks like coffee groundsĪpplies to apixaban: oral tablet.puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking apixaban: Rare ![]() Serious side effects of ApixabanĪlong with its needed effects, apixaban may cause some unwanted effects. Consider the benefits and risks of neuraxial intervention in patients who are or need to be anticoagulated. Monitor patients for signs and symptoms of neurologic impairment and treat urgently. The optimal timing between dosing apixaban and neuraxial procedures is unknown. In patients undergoing neuraxial anesthesia or spinal puncture, epidural or spinal hematoma risk is increased and could result in long-term or permanent paralysis. Consider an alternative anticoagulant if apixaban treatment is discontinued for any reason other than pathological bleeding or treatment completion. Premature discontinuation of apixaban or any oral anticoagulant increases the risk of thrombotic events. ![]()
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